Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery

COMPLETED

Identifier: CI-TRIAL-00032021
Entity page: /trial/NCT00194779 ↗
Edges: 15

Neighbours: 2 cancers10 drugs
Drawn: 12 of 12 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery condition of …CONDITION_OFderived5 of 5
← condition of	HER2-Positive Breast Carcinoma registry condition “HER2-positive Breast Cancer” mapped ALIAS	—	—	HER2-Positive Breast Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Malignant Breast Neoplasm registry condition “Stage IA Breast Cancer” mapped CURATED_BROADER

Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery intervention of …INTERVENTION_OFderived10 of 10
← intervention of	Capecitabinesmall molecule registry intervention “capecitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cyclophosphamidesmall molecule registry intervention “cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Doxorubicinsmall molecule registry intervention “doxorubicin hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Filgrastimother registry intervention “filgrastim” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Letrozolesmall molecule registry intervention “letrozole” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Methotrexatesmall molecule registry intervention “methotrexate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Paclitaxelsmall molecule registry intervention “paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Tamoxifensmall molecule registry intervention “tamoxifen citrate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “trastuzumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vinorelbinesmall molecule registry intervention “vinorelbine tartrate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery intervention of …INTERVENTION_OFderived10 of 10

← intervention of

Capecitabinesmall molecule

registry intervention “capecitabine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Cyclophosphamidesmall molecule

registry intervention “cyclophosphamide” (DRUG) mapped ALIAS

—