VEGFA

vascular endothelial growth factor A

Identifier: CI-GENE-00038355
Entity page: /gene/VEGFA ↗
Edges: 22

Neighbours: 1 cancers15 variants2 drugs
Drawn: 18 of 18 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
VEGFA associated with …ASSOCIATED_WITH1 of 1
→ associated with	Malignant Colorectal Neoplasmsubtype	supports	B	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
VEGFA targets …TARGETS2 of 2
← targets

VEGFA has variant …HAS_VARIANTderived15 of 19show all (up to 200)
→ has variant	Decreased Peri-therapeutic Expressionexpression 1 accepted CIViC evidence items	—	—	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
→ has variant	low ratio of VEGF165b/VEGFtotal no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.1032C>T (p.Ser344=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.*237C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.318del (p.Pro107fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.324del (p.Gln108fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.327del (p.Trp109fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.330del (p.Leu111fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.346C>G (p.Pro116Ala)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.350del (p.Gly117fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.367del (p.Ala123fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.403G>C (p.Ala135Pro)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.491del (p.Ser164fs)deletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_003376.6(VEGFA):c.506C>A (p.Ala169Glu)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Overexpressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

VEGFA has variant …HAS_VARIANTderived15 of 19show all (up to 200)

→ has variant

Decreased Peri-therapeutic Expressionexpression

1 accepted CIViC evidence items

—

Malignant Colorectal Neoplasm

Curated

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