PDGFB

platelet derived growth factor subunit B

Identifier: CI-GENE-00019273
Entity page: /gene/PDGFB ↗
Edges: 10

Neighbours: 1 cancers8 variants
Drawn: 9 of 9 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
PDGFB associated with …ASSOCIATED_WITH2 of 2
→ associated with	Dermatofibrosarcoma Protuberanssubtype 5 source records aggregated	supports	B	Dermatofibrosarcoma Protuberans	5	Curated	civic	graph →
→ associated with	Dermatofibrosarcoma Protuberanssubtype 2 source records aggregated

PDGFB has variant …HAS_VARIANTderived8 of 8
→ has variant	Fusionfusion 7 accepted CIViC evidence items	—	—	Dermatofibrosarcoma Protuberans	7	Curated	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.160+15C>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.250+67C>TSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.456+5G>ASNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.540T>G (p.Cys180Trp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.635C>T (p.Thr212Met)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_002608.4(PDGFB):c.670C>T (p.Arg224Trp)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Rearrangementstructural no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

PDGFB has variant …HAS_VARIANTderived8 of 8

→ has variant

Fusionfusion

7 accepted CIViC evidence items

—

Dermatofibrosarcoma Protuberans

Curated

civic

graph →

→ has variant

NM_002608.4(PDGFB):c.160+15C>ASNV

no accepted CIViC evidence item (variant record only)