NRG1

neuregulin 1

Identifier: CI-GENE-00017237
Entity page: /gene/NRG1 ↗
Edges: 28

Neighbours: 10 cancers15 variants
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
NRG1 associated with …ASSOCIATED_WITH12 of 12
→ associated with	Pancreatic Adenocarcinomasubtype	supports	A	Pancreatic Adenocarcinoma	1	Curated	civic	graph →
→ associated with	Lung Non-Small Cell Carcinomasubtype	supports	A

NRG1 has variant …HAS_VARIANTderived15 of 15
→ has variant	Expressionexpression 6 accepted CIViC evidence items	—	—	Malignant Neoplasm,Head and Neck Squamous Cell Carcinoma,Lung Non-Small Cell Carcinoma+2	6	Curated	civic	graph →
→ has variant	Fusionfusion 4 accepted CIViC evidence items	—	—	Lung Non-Small Cell Carcinoma,Pancreatic Adenocarcinoma	4	Curated	civic	graph →
→ has variant	Fusionfusion 2 accepted CIViC evidence items	—	—	Cholangiocarcinoma,Pancreatic Ductal Adenocarcinoma	2	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	not mapped	1	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	Pancreatic Ductal Adenocarcinoma	1	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	not mapped	1	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	Lung Adenocarcinoma	1	Curated	civic	graph →
→ has variant	e2::e4fusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	e3::e2fusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	e5::e4fusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Fusionfusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_013964.5(NRG1):c.1096G>T (p.Glu366Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_013964.5(NRG1):c.400+5G>CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NRG1 FUSIONSfusion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	OVEREXPRESSIONexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

NRG1 has variant …HAS_VARIANTderived15 of 15

→ has variant

Expressionexpression

6 accepted CIViC evidence items

—

Malignant Neoplasm,Head and Neck Squamous Cell Carcinoma,Lung Non-Small Cell Carcinoma+2

Curated

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