T Lymphoblastic Leukemia/Lymphoma

hematologic malignancy

Identifier: CI-CAN-00001560
Entity page: /cancer/t-lymphoblastic-leukemia-lymphoma ↗
Edges: 204

Neighbours: 1 genes1 variants16 drugs10 trials
Drawn: 28 of 28 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
T Lymphoblastic Leukemia/Lymphoma predicts response to …PREDICTS_RESPONSE_TO1 of 1
in context · predicts response to	CCND3 Lossdeletion_cna → predicts response to Palbociclib	sensitivity	D	T Lymphoblastic Leukemia/Lymphoma	1	Curated	civic	graph →
T Lymphoblastic Leukemia/Lymphoma associated with …

T Lymphoblastic Leukemia/Lymphoma investigated for …INVESTIGATED_FOR1 of 1
← investigated for	Palbociclibsmall_molecule	supports	D	T Lymphoblastic Leukemia/Lymphoma	1	Curated	civic	graph →

T Lymphoblastic Leukemia/Lymphoma investigated for …INVESTIGATED_FOR1 of 1

← investigated for

Palbociclibsmall_molecule

supports

T Lymphoblastic Leukemia/Lymphoma

Curated

T Lymphoblastic Leukemia/Lymphoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 61show all (up to 200)
→ investigated in trials for	Cyclophosphamidesmall molecule 27 trials (9 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	27	Observed	clinicaltrials	graph →
→ investigated in trials for	Dexamethasonesmall molecule 23 trials (10 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	23	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall molecule 23 trials (7 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	23	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall molecule 23 trials (8 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	23	Observed	clinicaltrials	graph →
→ investigated in trials for	Cytarabinesmall molecule 22 trials (9 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Pegaspargaseother 15 trials (6 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 14 trials (6 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	14	Observed	clinicaltrials	graph →
→ investigated in trials for	Mercaptopurinesmall molecule 13 trials (6 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Nelarabinesmall molecule 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Prednisonesmall molecule 13 trials (3 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Daunorubicinsmall molecule 11 trials (6 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 11 trials (2 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Leucovorinsmall molecule 11 trials (4 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Venetoclaxsmall molecule 11 trials (9 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	11	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall molecule 10 trials (3 active) · roll-up of the cancer and its descendants	—	—	T Lymphoblastic Leukemia/Lymphoma	10	Observed	clinicaltrials	graph →

T Lymphoblastic Leukemia/Lymphoma studied in …STUDIED_INderived10 of 140show all (up to 200)
→ studied in	NCT06738368Phase 2 · suspended Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06514794Phase 2 · recruiting A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex) · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06561074Phase 2 · recruiting A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy) · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT05289687Phase 2 · recruiting Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04128501Phase 2 · active not recruiting Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04972942Phase 1 · recruiting Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphoma · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04315324Phase 1/Phase 2 · active not recruiting Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL) · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06648889Phase 2 · recruiting Isatuximab in Adult Patients With Cytologic or Molecular Relapsed/Refractory CD38 Positive T-cell Acute Lymphoblastic Leukemia · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00792948Phase 2 · active not recruiting Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia · condition mapped ONTOLOGY_EXACT · 140 trials mapped (58 active)	—	—	Adult T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04033302Phase 1/Phase 2 · not yet recruiting Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies · condition mapped CURATED_BROADER · 140 trials mapped (58 active)	—	—	T Acute Lymphoblastic Leukemia	1	Observed	clinicaltrials	graph →

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