Paget Disease — knowledge graph · CancerIndex

Knowledge graph · Cancer

Paget Disease

histology

Identifier: CI-CAN-00003559
Entity page: /cancer/paget-disease ↗
Edges: 27

Neighbours: 7 drugs10 trials
Drawn: 17 of 17 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Paget Disease approved for …APPROVED_FOR1 of 1
← approved for	Zoledronic Acidsmall_molecule	supports	FDA ORIG	Paget Disease	1	Regulatory	openfda	graph →
Paget Disease investigated in trials for …INVESTIGATED_IN_TRIALSderived6 of 6

Paget Disease studied in …STUDIED_INderived10 of 20show all (up to 200)
→ studied in	NCT02978625Phase 2 · active not recruiting Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers · condition mapped ONTOLOGY_EXACT · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT05859074Phase 1 · recruiting A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer · condition mapped ONTOLOGY_EXACT · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT02834013Phase 2 · active not recruiting Nivolumab and Ipilimumab in Treating Patients With Rare Tumors · condition mapped ONTOLOGY_EXACT · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT03713203NA · recruiting PAGETEX® Photodynamic Therapy Device for the Treatment of Extra Mammary Paget's Disease of the Vulva (EMPV). · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Vulvar Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT03564483recruiting Gynecologic Extramammary Paget's Disease · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT06873815Phase 2 · recruiting A Study of Fluorescein Sodium in People Undergoing Vulvectomy for Extramammary Paget's Disease (EMPD) · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT06683846Phase 2 · recruiting Ivonescimab in the Treatment of Multiple Advanced Tumors · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT07117851Phase 2 · recruiting A Study of Disitamab Vedotin + Bicalutamide in HER2/AR-Positive Scrotal Paget's Disease · condition mapped ONTOLOGY_EXACT · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT06715592Phase 2 · active not recruiting ECT STUDY High-grade or Initially Invasive Vulva - GinOnc-ECT Study · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Vulvar Paget Disease	1	Observed	clinicaltrials	graph →
→ studied in	NCT06791070Phase 2 · recruiting A Study of RC48-ADC Combined With JS001 for Advanced Extramammary Paget Disease of the Scrotum · condition mapped ALIAS · 20 trials mapped (11 active)	—	—	Extramammary Paget Disease	1	Observed	clinicaltrials	graph →