Clinical trial · Observational
Gynecologic Extramammary Paget's Disease
Prospective Registry of Gynecologic Patients With Extramammary Paget's Disease
NCT03564483CI-TRIAL-00101833recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In addition to evaluating treatment outcomes, tissue samples and swabs will be collected as part of this study to allow physicians to better understand Extramammary Paget's Disease (EMPD). The researchers also want to learn more about the microorganisms (microbiome) that live on or near the areas of skin affected by EMPD, in order to better understand this condition.
Conditions
Conditions (9)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Extramammary Paget Disease | Extramammary Paget Disease | ONTOLOGY_EXACT | 0.98 |
| Extramammary Paget's Disease | Extramammary Paget Disease | ALIAS | 0.90 |
| Extramammary Paget's Disease of Anal Canal (Diagnosis) | — | UNRESOLVED | — |
| Extramammary Paget's Disease of Anus (Diagnosis) | — | UNRESOLVED | — |
| Extramammary Paget's Disease of Skin | — | UNRESOLVED | — |
| Extramammary Paget's Disease of Vagina (Diagnosis) | — | UNRESOLVED | — |
| Extramammary Paget's Disease of Vulva (Diagnosis) | — | UNRESOLVED | — |
| Extramammary Paget's Disease Vulva Invasive | — | UNRESOLVED | — |
| Paget Disease, Extramammary | Extramammary Paget Disease | ALIAS |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- Registry Observational Study
- description
- All women presenting for evaluation of Extramammary Paget's Disease (EMPD) at Mayo Clinic in Rochester MN.
Primary outcomes (1)
- measure
- Collect prospective data including outcomes and long-term survival in women with extramammary Paget's disease (EMPD).
- timeFrame
- 25 years
- description
- Prospective data including patient demographic information, surgical outcomes, surgical morbidity, recurrence, and long-term survival in extramammary Paget's disease (EMPD) will be collected as part of this registry..
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Females * Age 18 years or older * Diagnosed with primary or recurrent EMPD of vulva and/or perianal region of the body * Willing and able to provide signed informed consent Exclusion Criteria: * Males * Diagnosis of Paget's Disease in body areas other than vulvar or perianal region
References
Publications (1)
- DERIVEDBruce KH, Kilts TP, Lohman ME, Vidal NY, Fought AJ, McGree ME, Keeney GL, Baum CL, Brewer JD, Bakkum-Gamez JN, Cliby WA. Mohs surgery for female genital Paget's disease: a prospective observational trial. Am J Obstet Gynecol. 2023 Dec;229(6):660.e1-660.e8. doi: 10.1016/j.ajog.2023.08.018. Epub 2023 Aug 24. PMID 37633576