Non-Clear Cell Renal Cell Carcinoma

subtype

Identifier: CI-CAN-00008117
Entity page: /cancer/non-clear-cell-renal-cell-carcinoma ↗
Edges: 299

Neighbours: 15 genes15 drugs10 trials
Drawn: 40 of 40 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Non-Clear Cell Renal Cell Carcinoma altered in cohorts of …ALTERED_INderived15 of 202show all (up to 200)
← altered in cohorts of	GPRIN2 61 / 86 cases (71 %) · ssm · TCGA-KICH	—	—	Chromophobe Renal Cell Carcinoma	1	Observed	gdc	graph →
← altered in cohorts of	MUC4 46 / 66 cases (70 %) · ssm · kich_tcga

Non-Clear Cell Renal Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 35show all (up to 200)
→ investigated in trials for	Nivolumabmonoclonal antibody 15 trials (14 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	15	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabozantinibsmall molecule 13 trials (11 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 10 trials (9 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Sunitinibsmall molecule 6 trials (3 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 4 trials (4 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Atezolizumabmonoclonal antibody 3 trials (3 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Axitinibsmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Savolitinibsmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Sorafenib Tosylatesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Everolimussmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Pazopanibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Prednisonesmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Non-Clear Cell Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →

Non-Clear Cell Renal Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 35show all (up to 200)

→ investigated in trials for

Nivolumabmonoclonal antibody

15 trials (14 active) · roll-up of the cancer and its descendants

—

Non-Clear Cell Renal Cell Carcinoma

Observed

Non-Clear Cell Renal Cell Carcinoma studied in …STUDIED_INderived10 of 62show all (up to 200)
→ studied in	NCT03866382Phase 2 · recruiting Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Chromophobe Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04981509Phase 2 · recruiting Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Papillary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04071223Phase 2 · active not recruiting Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Chromophobe Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07024680completed Real World Study of Effectiveness of Sunitinib or Sorafenib to Chinese Unresectable Locally Advanced or Metastatic PRCC · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Papillary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03635892Phase 2 · active not recruiting A Study of Nivolumab In Combination With Cabozantinib in Patients With Non-Clear Cell Renal Cell Carcinoma · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Papillary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05831891Phase 2 · active not recruiting Fruquintinib Plus Serplulimab as First-Line Therapy for Metastatic Non-Clear Cell Renal Cell Carcinoma · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Non-Clear Cell Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07816770Phase 2 · not yet recruiting MANTIS-RCC: Toripalimab-Axitinib Induction in TLS-Positive Advanced Non-Clear Cell and Renal Medullary Carcinomas · condition mapped CURATED_BROADER · 62 trials mapped (38 active)	—	—	Non-Clear Cell Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02496208Phase 1 · active not recruiting Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Sarcomatoid Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05411081Phase 2 · active not recruiting Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial · condition mapped CURATED_BROADER · 62 trials mapped (38 active)	—	—	Papillary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03793166Phase 3 · active not recruiting Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study · condition mapped ONTOLOGY_EXACT · 62 trials mapped (38 active)	—	—	Sarcomatoid Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →

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