| Malignant Rectal Neoplasm studied in …STUDIED_INderived200 of 1,551show all (up to 200) |
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| → studied in | NCT02465060Phase 2 · active not recruiting Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04751370Phase 2 · active not recruiting Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07346586NA · recruiting Tamsulosin for Early Catheter Removal After Rectal Cancer Surgery · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07846046NA · not yet recruiting Endoscopic (EID) Versus Surgical (TAMIS) Local Excision for Early Stage Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07847229Phase 2 · not yet recruiting A Prospective, Biomarker-Stratified Phase 2 Study: β-Hydroxybutyrate as a Predictive Biomarker for Short-Course Radiotherapy Followed by Chemotherapy Plus PD-1 Inhibitor Versus Chemotherapy Alone in Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03623464NA · suspended RCT of Mobile Apps & FitBit v. Usual Care · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06958432Phase 2/Phase 3 · recruiting Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06997497Phase 3 · recruiting A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012) · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03516942active not recruiting Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05513742Phase 2 · completed A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05610163Phase 2/Phase 3 · active not recruiting Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation and Continuing Response · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02293954NA · active not recruiting Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05752136Phase 3 · recruiting Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06337552NA · active not recruiting High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06843655active not recruiting Radiological Markers in Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07227636Phase 2 · recruiting A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07833319Phase 2 · recruiting Local Methylene Blue Injection for Prevention of Anastomotic Leakage and Permanent Stoma After Low Anterior Resection for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07132463Phase 3 · recruiting Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07200141Phase 2 · recruiting Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02874885active not recruiting Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07622771Phase 2 · recruiting Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical Trial · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07780305not yet recruiting ABCSG R07 Rectal Cancer Registry · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05081024recruiting Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06459869Phase 1 · active not recruiting NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02381561Phase 1 · active not recruiting Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04165772Phase 2 · recruiting Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06146946NA · recruiting Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06246344Phase 3 · active not recruiting Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06263088NA · recruiting EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer. · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07769853NA · not yet recruiting Iparomlimab and Tuvonralimab Combined With Chemotherapy and Bevacizumab as Neoadjuvant Therapy for Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05059444recruiting ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05482516Phase 3 · recruiting Evaluating Novel Therapies in ctDNA Positive GI Cancers · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07098182NA · recruiting Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07404228not yet recruiting Multidimensional Study Designed to Develop a Methodological Framework Based on MRI Data to Predict Pathological Complete Response (pCR) in Patients With Locally Advanced Rectal Cancer After Neoadjuvant Treatment · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07786493NA · recruiting HDR Endorectal Brachytherapy With 3D-Printed Guidance and Local Shielding for Rectal Cancer Organ Preservation · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07799740NA · not yet recruiting Examination of Rectal Blood Supply During Rectal Cancer Surgery Using Laser Speckle Contrast Imaging · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04674267NA · recruiting Resilience and Equity in Aging, Cancer, and Health (REACH) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07805369Phase 1 · not yet recruiting A Phase 1 Study of DEM301 in Participants With Metastatic Colorectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07810114Phase 2 · not yet recruiting Total Neoadjuvant mFOLFOX6 Plus Suvemcitug and Enlonstobart With Selective Omission of Pelvic Radiotherapy for High-Risk Mid-Rectal Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07811076Phase 1/Phase 2 · not yet recruiting Serine/Glycine-Restricted Diet With Chemoradiotherapy for Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07811128not yet recruiting Leveraging Digital Health Solutions to Collect Patient-Reported Outcomes in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07779694Phase 2 · not yet recruiting 16-Hour Fasting Plus Serplulimab and CAPEOX as Neoadjuvant Therapy in pMMR/MSS Advanced Mid-to-Low Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07802197NA · recruiting Neoadjuvant Radiotherapy vs Upfront Surgery in Locally Advanced Proximal Rectal Cancer · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04749108Phase 2/Phase 3 · recruiting Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05080673NA · recruiting Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05585814Phase 2 · active not recruiting CapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Microsatellite Stable Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05868226Phase 1/Phase 2 · recruiting PRE-ISPY Phase I/II Oncology Platform Program · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06904365recruiting Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06929338withdrawn xDRIVE in Metastatic Colorectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07143487NA · recruiting Family Communications After Genetic Testing · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07283939NA · recruiting Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07292298Phase 2 · recruiting Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02997553Phase 3 · completed Fluorescence for Sentinel Lymph Node Identification in Cancer Surgery · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05627635Phase 1/Phase 2 · active not recruiting FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02107105recruiting Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05652361NA · recruiting Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00712751completed The Sexual Health of Rectal Cancer Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07341126not yet recruiting Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02008656Phase 2 · active not recruiting Trial Evaluating 3-year Disease Free Survival in Patients With Locally Advanced Rectal Cancer Treated With Chemoradiation Plus Induction or Consolidation Chemotherapy and Total Mesorectal Excision or Non-operative Management · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03190941Phase 1/Phase 2 · recruiting Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07781774NA · not yet recruiting Improving Colorectal Cancer Screening Uptake Through Education and Stool-Based Testing Outreach · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05254327Phase 2 · recruiting Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001 · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07774754Phase 2 · not yet recruiting Radiotherapy Combined With Capeox Chemotherapy, Sintilimab and Suvemcitug in Locally Advanced pMMR Rectal Cancer:a Prospective Clinical Trial · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03573791recruiting Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07735624Phase 2 · recruiting RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04246684Phase 3 · active not recruiting Short RT Versus RCT,Followed by Chemo and Organ Preservation for Interm and High-risk Rectal Cancer Patients · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04942626Phase 1 · completed Capecitabine-based Chemoradiotherapy in Combination With the IL-1 Receptor Antagonist Anakinra for Rectal Cancer Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07765667Phase 2 · not yet recruiting NCT + PD1 + Ketogenic Diet and/or Vitamin C for LARC · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05722288Phase 2 · active not recruiting Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07764120not yet recruiting Quality of Life of Patients After Rectal Cancer Resection . · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07761169NA · not yet recruiting Randomized Controlled Trial of the SurgDiff Model for Predicting Surgical Difficulty to Help Choose Approach in Mid-Low Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT00648635active not recruiting Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04525989NA · recruiting Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06501053NA · recruiting Contact Radiotherapy for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06577194Phase 2 · active not recruiting Neoadjuvant Short-Course Radiotherapy Followed by CAPOX Plus PD-1 Antibody and IL-2 in Locally Advanced Rectal Cancer (PRIDE01) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07162714Phase 2 · recruiting SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04104139Phase 1 · completed TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05524012active not recruiting Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07059884NA · recruiting Distance-Based Exercise to Preserve Function and Prevent Disability · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07209215Phase 2 · not yet recruiting ctDNA-Informed Management of Early-Stage Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05111574Phase 2 · active not recruiting Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06908031Phase 2 · completed SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06052332NA · recruiting Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06210971Phase 2 · active not recruiting Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06949098Phase 2 · recruiting Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05715255NA · active not recruiting Adaptive Symptom Self-Management Immunotherapy Study · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07057089Phase 2 · suspended Involved-field Radiotherapy-TNT Combined With PD-1 Inhibitor for pMMR Locally Advanced Rectal Cancer (Neo-Field I) · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03068403NA · terminated Dynamic Contrast Enhanced Ultrasound for Predict and Assess Rectal Cancer Response After Neo-adjuvant Chemoradiation - RECT · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07736131completed Learning Curve of SILS in CRC · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07738042NA · not yet recruiting To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05024097Phase 2 · recruiting A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer. · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06802172NA · recruiting Effect of Meal Timing During Cancer Treatment in Patients in Alaska: A Randomized Clinical Trial · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07732894NA · recruiting Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04098471NA · recruiting Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05009069Phase 2 · active not recruiting A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07580339Phase 2 · not yet recruiting Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07726966NA · not yet recruiting Betacyanin for Early Diagnosis and Recovery of Anastomotic Leakage After Rectal Cancer Surgery: A Single-Center, Prospective, Controlled Trial · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01696981NA · active not recruiting Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial) · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04677413Phase 1 · active not recruiting Ultra-fractionated Radiotherapy for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05253846Phase 2 · active not recruiting Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07104604Phase 2 · recruiting Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07118800Phase 3 · not yet recruiting Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03941366NA · terminated Treatment of Adenocarcinoma of the Rectum With Transanal Local Excision for Complete Responders · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05526079NA · terminated Watchful Waiting for Complete Responders to Therapy in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06834126Phase 1 · recruiting Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04599140Phase 1/Phase 2 · active not recruiting SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07711509NA · active not recruiting Autologous Fecal Microbiota Transplantation for Anal Function Recovery After Ileostomy Reversal in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05400122Phase 1 · suspended Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06205485Phase 3 · recruiting Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06340646NA · recruiting Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04815694NA · recruiting THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05538195Phase 1/Phase 2 · completed Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07695519not yet recruiting SCARLET - Italian proSpeCtionAl obseRvationaL multicEntre Study on Treatment for recTal pT1 Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05054959Phase 2 · active not recruiting Consolidation Versus Induction Chemotherapy in Total Neoadjuvant Therapy of Rectal Cancer With High Risk for Recurrence · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07691489Phase 2 · not yet recruiting A Study of Trastuzumab Deruxtecan (T-DXd) and Cetuximab in People With Colorectal Cancer · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03879109Phase 3 · completed Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05308446Phase 2 · active not recruiting Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06933251Phase 2 · active not recruiting PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03345563NA · completed Project HERO: Health Empowerment & Recovery Outcomes · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05507112Phase 2 · active not recruiting TIME in Immunotherapy Combined With nCRT for Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07688135NA · not yet recruiting Quicksilver II Pilot Study · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04184973NA · recruiting Efficacy and Safety of the CG-100 Intraluminal Bypass Device · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01871571Phase 2 · terminated Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04643366Phase 2 · recruiting Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05629442not yet recruiting ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06364384Phase 2 · recruiting Radical Concurrent Chemoradiotherapy With DDP/5-FU and PD-1 Antibody for Non-metastatic Rectal Squamous Cell Carcinoma · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07549399Phase 3 · recruiting SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07595874Phase 2 · recruiting Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03051464Phase 2/Phase 3 · recruiting Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06507371Phase 3 · active not recruiting Node-sparing Short-Course Radiation Combined With CAPOX and Tislelizumab for MSS Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02012699recruiting Integrated Cancer Repository for Cancer Research · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02945566Phase 2/Phase 3 · active not recruiting Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer? · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06780787Phase 2 · recruiting FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07669220Phase 2 · recruiting A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial) · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07669298NA · recruiting Active Surveillance vs Adjuvant Chemoradiotherapy for Locally Resected Intermediate-Risk T1 Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06884670Phase 2 · completed Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04323722NA · completed Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04929028Phase 2 · active not recruiting Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05772481recruiting Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07209787Phase 4 · recruiting SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07596290Phase 2/Phase 3 · not yet recruiting Yang et al. Anti-PD-1/CTLA-4 Dual Immunotherapy for LARC · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05038254NA · active not recruiting Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06843434Phase 2 · recruiting A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Microsatellite Stable Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07651007Phase 2 · not yet recruiting Short-course RT Followed by NALIRIFOX Plus Pucotenlimab as Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer With MSS/pMMR · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05943210NA · recruiting The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07646639Phase 2 · recruiting Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01148056NA · terminated Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04616183Phase 1/Phase 2 · active not recruiting LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06051695Phase 1/Phase 2 · recruiting A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07011576Phase 2 · recruiting A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07645118Phase 2 · not yet recruiting Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04017650Phase 1/Phase 2 · active not recruiting Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04804956recruiting Mesorectal Microbiome and Metabolome as a Prognostic Factor in Patients With Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07188025Phase 3 · recruiting ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07292285withdrawn The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial. · condition mapped ALIAS · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07306390not yet recruiting Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07467434recruiting FOLFIRINOX Induction Chemotherapy for Synchronous Liver Metastases · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05245786early Phase 1 · active not recruiting An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05331040withdrawn Radiomics in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03781323Phase 2 · active not recruiting Neoadjuvant FOLFOX Therapy With Short Course Radiation and Active Surveillance in Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07281157Phase 2 · recruiting Liposomal Irinotecan, Capecitabine and Enlonstobart With Short-Course Radiotherapy for Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05007015NA · active not recruiting Transanal Irrigation for the Management of LARS · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05056077NA · active not recruiting Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit) · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06637462NA · recruiting A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07619768NA · completed Self Regulation Hypnotic Intervention for Pain and Anxiety During Rectal Brachytherapy · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07622017Phase 2 · not yet recruiting KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07616297NA · recruiting Higher Radiation Dose to the Tumor May Help Avoid Surgery in Rectal Cancer Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02403505Phase 1 · active not recruiting Early Phase Clinical Trial About Therapeutic Biological Product Mix for Treating CEA Positive Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07176182Phase 2 · recruiting Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07605611NA · recruiting Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03548961Phase 2 · active not recruiting Organ Preservation in Early Rectal Cancer Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04503694Phase 2 · active not recruiting Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03594630early Phase 1 · recruiting Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03745326Phase 1/Phase 2 · terminated Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07594925Phase 2 · recruiting Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07595107not yet recruiting Concordance Between Large Language Model and Multidisciplinary Team Recommendations in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07596732NA · not yet recruiting Statewide Unified Network for Remote Intervention of Strength and Exercise · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07581626Phase 2 · not yet recruiting Short-Course Online Adaptive Radiotherapy Combined With Chemotherapy, Targeted Therapy and Immunotherapy as Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02514278Phase 3 · completed Optimisation of Response for Organ Preservation in Rectal Cancer : Neoadjuvant Chemotherapy and Radiochemotherapy vs. Radiochemotherapy · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05877352NA · active not recruiting Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06673329Phase 1 · recruiting Brodalumab in the Treatment of Immune-Related Adverse Events · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07113275Phase 3 · recruiting A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05672524Phase 2 · recruiting A Study of Tucatinib and Trastuzumab in People With Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06123156Phase 3 · recruiting Interest of Early Erectile Rehabilitation With Sildenafil After Radiotherapy and Proctectomy for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07580027NA · not yet recruiting Preoperative, Adaptive Radiotherapy Concomitant to Chemotherapy for Rectal Adenocarcinoma (Adaptive Rectal Cancer Trial 02) · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06758830Phase 2/Phase 3 · recruiting Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07253298NA · enrolling by invitation The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04864067Phase 2 · completed No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06149741NA · terminated Defunctioning Left-sided Colostomy in Low Anterior Resection for Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04713618active not recruiting Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy · condition mapped ONTOLOGY_EXACT · 1,551 trials mapped (487 active) | — | — | Rectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06189846completed Lumeneye Rectoscope for Assessment on Tumor Response After Total Neoadjuvant Treatment in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03874559recruiting Exosomes in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04130854Phase 2 · completed INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Rectal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06239194Phase 1/Phase 2 · recruiting Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06936774Phase 3 · recruiting Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & Surveillance · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06249672recruiting Longterm Functional Outcomes in Patients Undergoing Organ Preserving Treatment for Rectal Cancer With or Without Local Excision After Chemoradiotherapy · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07454720Phase 2/Phase 3 · recruiting A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07566559recruiting Rectal Cancer Neoadjuvant Therapy-Real World Study · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07552207NA · not yet recruiting Comparison of [68Ga]Ga-CTR-FAPI and 18F-FDG PET/MRI for Lymph Node Staging in Rectal Cancer · condition mapped CURATED_EXACT · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07563907NA · not yet recruiting Total Neoadjuvant Therapy With Additional Consolidation Chemotherapy Followed by Local Excision Versus Total Neoadjuvant Therapy Followed by Local Excision at Stage I Rectal Cancer · condition mapped CURATED_BROADER · 1,551 trials mapped (487 active) | — | — | Malignant Rectal Neoplasm | 1 | Observed | clinicaltrials | graph → |