Diffuse Intrinsic Pontine Glioma

Observed

→ investigated in trials for

Everolimussmall_molecule

6 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal_antibody

5 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cyclophosphamidesmall molecule

4 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Irinotecansmall molecule

4 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ribociclibsmall_molecule

4 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dordavipronesmall molecule

3 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Etoposidesmall molecule

3 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal_antibody

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Panobinostatsmall_molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dasatinibsmall_molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Erlotinibsmall_molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Gemcitabinesmall molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nimotuzumabmonoclonal_antibody

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Topotecansmall molecule

2 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vorinostatsmall_molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Abemaciclibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Adavosertibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Carboplatinsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cemiplimabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Crenolanibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Crizotinibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dostarlimabmonoclonal antibody

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Doxorubicinsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

FACT Complex-targeting Curaxin CBL0137

→ investigated in trials for

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Imiquimodsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Larotrectinibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lenalidomidesmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lomustinesmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lorlatinibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lutetium (177lu) Oxodotreotideother

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Melphalansmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Palbociclibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal antibody

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Savolitinibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Temsirolimussmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Tovorafenibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Valproic Acidsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vincristinesmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Vinorelbinesmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Diffuse Intrinsic Pontine Glioma studied in …STUDIED_INderived10 of 111show all (up to 200)
→ studied in	NCT05298995Phase 1 · recruiting GD2-CAR T Cells for Pediatric Brain Tumours · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01445288completed Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04837547Phase 1 · active not recruiting PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06838676Phase 2 · recruiting ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas · condition mapped ALIAS · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04870944Phase 1/Phase 2 · recruiting CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma · condition mapped CURATED_BROADER · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06639607Phase 1/Phase 2 · suspended PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma · condition mapped PROBABILISTIC · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06946680Phase 1 · not yet recruiting IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07644312Phase 2 · not yet recruiting Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05839379recruiting Targeted Pediatric High-Grade Glioma Therapy · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06465199Phase 1/Phase 2 · recruiting Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)	—	—	Diffuse Intrinsic Pontine Glioma	1	Observed	clinicaltrials	graph →

Diffuse Intrinsic Pontine Glioma studied in …STUDIED_INderived10 of 111show all (up to 200)

→ studied in

NCT05298995Phase 1 · recruiting

GD2-CAR T Cells for Pediatric Brain Tumours · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT01445288completed

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT04837547Phase 1 · active not recruiting

PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT06838676Phase 2 · recruiting

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas · condition mapped ALIAS · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT04870944Phase 1/Phase 2 · recruiting

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma · condition mapped CURATED_BROADER · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT06639607Phase 1/Phase 2 · suspended

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma · condition mapped PROBABILISTIC · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT06946680Phase 1 · not yet recruiting

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG) · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT07644312Phase 2 · not yet recruiting

Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed

→ studied in

NCT05839379recruiting

Targeted Pediatric High-Grade Glioma Therapy · condition mapped ONTOLOGY_EXACT · 111 trials mapped (52 active)

—

Observed