Chronic Eosinophilic Leukemia, Not Otherwise Specified

hematologic malignancy

Identifier: CI-CAN-00002361
Entity page: /cancer/chronic-eosinophilic-leukemia-not-otherwise-specified ↗
Edges: 43

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Chronic Eosinophilic Leukemia, Not Otherwise Specified approved for …APPROVED_FOR3 of 3
← approved for	Imatinibsmall_molecule 2 source records aggregated	supports	FDA ORIG	Chronic Eosinophilic Leukemia, Not Otherwise Specified	2	Regulatory	openfda	graph →
← approved for	Imatinib Mesylatesmall_molecule

Chronic Eosinophilic Leukemia, Not Otherwise Specified investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 15
→ investigated in trials for	Fludarabinesmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Imatinibsmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Akt Inhibitor MK2206 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Azacitidinesmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cytarabinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Imatinib Mesylatesmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Ruxolitinibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Sunitinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Venetoclaxsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →

Chronic Eosinophilic Leukemia, Not Otherwise Specified investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 15

→ investigated in trials for

Fludarabinesmall molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Chronic Eosinophilic Leukemia, Not Otherwise Specified

Observed

Chronic Eosinophilic Leukemia, Not Otherwise Specified studied in …STUDIED_INderived10 of 25show all (up to 200)
→ studied in	NCT03801434Phase 2 · active not recruiting Ruxolitinib in Treating Patients With Hypereosinophilic Syndrome or Primary Eosinophilic Disorders · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT03862157Phase 1/Phase 2 · active not recruiting Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT01384513Phase 2 · completed A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT01199562active not recruiting Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT02760238recruiting Myeloproliferative Neoplasms (MPNs) Patient Registry · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT01588015Phase 1 · completed Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT00489203Phase 2 · completed Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT00856388NA · completed Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT01305200Phase 3 · completed Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →
→ studied in	NCT01159067Phase 2 · terminated Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload · condition mapped ONTOLOGY_EXACT · 25 trials mapped (4 active)	—	—	Chronic Eosinophilic Leukemia, Not Otherwise Specified	1	Observed	clinicaltrials	graph →

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