Childhood Medulloblastoma

subtype

Identifier: CI-CAN-00002289
Entity page: /cancer/childhood-medulloblastoma ↗
Edges: 92

Neighbours: 1 genes1 variants15 drugs10 trials
Drawn: 27 of 27 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Medulloblastoma diagnostic of …DIAGNOSTIC_OF1 of 1
← diagnostic of	CTNNB1 Exon 3 Mutation 2 source records aggregated	supports	B	Childhood Medulloblastoma	2	Curated	civic	graph →
Childhood Medulloblastoma associated with …ASSOCIATED_WITH1 of 1
associated with

Childhood Medulloblastoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 34show all (up to 200)
→ investigated in trials for	Temozolomidesmall molecule 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Irinotecansmall molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Topotecansmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vismodegibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Alvocidibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Bortezomibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →

Childhood Medulloblastoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 34show all (up to 200)

→ investigated in trials for

Temozolomidesmall molecule

6 trials (2 active) · roll-up of the cancer and its descendants

—

Childhood Medulloblastoma studied in …STUDIED_INderived10 of 56show all (up to 200)
→ studied in	NCT07346157Phase 1/Phase 2 · recruiting Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05230758Phase 3 · recruiting Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07830134NA · recruiting Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic Neurofeedback · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03210714Phase 2 · active not recruiting Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) · condition mapped CURATED_BROADER · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06959979early Phase 1 · recruiting Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07390539Phase 1 · recruiting B7-H3.CD28Z.CART in CNS Neoplasms · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05382338Phase 3 · recruiting A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05057702NA · recruiting Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06942039early Phase 1 · recruiting Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06193759Phase 1 · recruiting Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) · condition mapped ONTOLOGY_EXACT · 56 trials mapped (14 active)	—	—	Childhood Medulloblastoma	1	Observed	clinicaltrials	graph →

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