Childhood Acute Promyelocytic Leukemia — knowledge graph · CancerIndex

Knowledge graph · Cancer

Childhood Acute Promyelocytic Leukemia

hematologic malignancy

Identifier: CI-CAN-00008787
Entity page: /cancer/childhood-acute-promyelocytic-leukemia ↗
Edges: 25

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Acute Promyelocytic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 15
→ investigated in trials for	Methotrexatesmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Acute Promyelocytic Leukemia	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Arsenic Trioxidesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants

Childhood Acute Promyelocytic Leukemia studied in …STUDIED_INderived10 of 10
→ studied in	NCT00866918Phase 3 · completed Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia · condition mapped ALIAS · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT02200978Phase 4 · completed A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01445080Phase 1/Phase 2 · completed Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia · condition mapped ALIAS · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT01869803approved for marketing Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01146223completed Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00217412Phase 1 · completed Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00003934Phase 3 · completed Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00077467Phase 1 · completed Bortezomib in Treating Young Patients With Refractory or Recurrent Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00042796Phase 1 · terminated Decitabine in Treating Children With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01177371Phase 2 · completed High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma · condition mapped ONTOLOGY_EXACT · 10 trials mapped (0 active)	—	—	Childhood Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →