Clinical trial · Observational
Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic Leukemia
Observational - WT-1's Role in Leukemogenesis
NCT01146223CI-TRIAL-00017830completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study is studying biomarkers in patients with acute promyelocytic leukemia. Studying samples of bone marrow from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and about biomarkers related to cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia | ONTOLOGY_EXACT | 0.98 |
| Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) | — | UNRESOLVED | — |
| Adult Acute Promyelocytic Leukemia (M3) | Adult Acute Promyelocytic Leukemia | ONTOLOGY_EXACT | 0.85 |
| Childhood Acute Promyelocytic Leukemia (M3) | Childhood Acute Promyelocytic Leukemia | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Basic science (correlative studies)
- description
- Patient mRNA samples from diagnosis are analyzed via quantitative PCR to measure WT1 and VEGF-1 expression.
- interventionNames
- Other: laboratory biomarker analysis
Primary outcomes (1)
- measure
- WT1 and VEGF-1 expression
- timeFrame
- Baseline
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of acute promyelocytic leukemia \[t(15;17) translocation\] * Not specified * Not specified
References
Publications (0)
Data not yet available
No reference posted for this study.