Cervical Squamous Neoplasm

subtype

Identifier: CI-CAN-00000668
Entity page: /cancer/cervical-squamous-neoplasm ↗
Edges: 180

Neighbours: 15 genes15 drugs10 trials
Drawn: 40 of 40 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Cervical Squamous Neoplasm altered in cohorts of …ALTERED_INderived15 of 47show all (up to 200)
← altered in cohorts of	TTN 91 / 291 cases (31 %) · ssm · cesc_tcga_pan_can_atlas_2018 · largest of 3 cohorts	—	—	Cervical Squamous Cell Carcinoma	3	Observed	cbioportal	graph →
← altered in cohorts of	PIK3CA 83 / 291 cases (29 %) · ssm · cesc_tcga_pan_can_atlas_2018 · largest of 3 cohorts

Cervical Squamous Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 35show all (up to 200)
→ investigated in trials for	Cisplatinsmall molecule 24 trials (5 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	24	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall molecule 10 trials (2 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 7 trials (2 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Nimotuzumabmonoclonal antibody 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Atezolizumabmonoclonal antibody 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal antibody 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 3 trials (3 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Topotecansmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fluorouracilsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Gemcitabinesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Nab-paclitaxel 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Cervical Squamous Neoplasm	2	Observed	clinicaltrials	graph →

Cervical Squamous Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 35show all (up to 200)

→ investigated in trials for

Cisplatinsmall molecule

24 trials (5 active) · roll-up of the cancer and its descendants

—

Cervical Squamous Neoplasm

Observed

Cervical Squamous Neoplasm studied in …STUDIED_INderived10 of 98show all (up to 200)
→ studied in	NCT07061977Phase 3 · recruiting Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07848243Phase 2 · recruiting Clinical Investigator-Initiated Trial (IIT) of PD-L1-Targeted Radionuclide Probes · condition mapped ALIAS · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07147361active not recruiting Predictive Biomarkers for PD-1 Inhibitor Response in Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07217171Phase 1 · recruiting A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03074513Phase 2 · active not recruiting Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors · condition mapped ONTOLOGY_EXACT · 98 trials mapped (24 active)	—	—	Human Papillomavirus-Related Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07602842Phase 1/Phase 2 · recruiting A Study of IDP-001 in Advanced or Metastatic Solid Tumors · condition mapped ALIAS · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07796672recruiting Feasibility Study of Blood Biomarker Identification in Cervical Cancer · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02466971Phase 3 · active not recruiting Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05827614Phase 1 · terminated Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene Amplifications · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06543576Phase 1/Phase 2 · recruiting External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer · condition mapped CURATED_BROADER · 98 trials mapped (24 active)	—	—	Cervical Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →

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