Breast Lobular Carcinoma

subtype

Identifier: CI-CAN-00004683
Entity page: /cancer/breast-lobular-carcinoma ↗
Edges: 104

Neighbours: 18 drugs10 trials
Drawn: 28 of 28 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Breast Lobular Carcinoma investigated for …INVESTIGATED_FOR5 of 5
← investigated for	Fulvestrantsmall_molecule	unknown	3	Breast Lobular Carcinoma	1	Curated	chembl	graph →
← investigated for	Anastrozolesmall_molecule	unknown	3

Breast Lobular Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived18 of 18show fewer
→ investigated in trials for	Tamoxifensmall molecule 7 trials (3 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Letrozolesmall_molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Anastrozolesmall_molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fulvestrantsmall_molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Abemaciclibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Bexarotenesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Chemotherapy 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Crizotinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Entrectinibsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Exemestanesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Goserelinother 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Hormone Therapy 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Metforminsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Neratinibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Repotrectinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Ruxolitinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →

Breast Lobular Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived18 of 18show fewer

→ investigated in trials for

Tamoxifensmall molecule

7 trials (3 active) · roll-up of the cancer and its descendants

—

Breast Lobular Carcinoma

Observed

Breast Lobular Carcinoma studied in …STUDIED_INderived10 of 81show all (up to 200)
→ studied in	NCT07842055completed AI-based Prognostic Factors Identification in Early-stage Invasive Lobular Breast Carcinoma · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04570956Phase 2 · terminated Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk · condition mapped ONTOLOGY_EXACT · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT07408856Phase 1 · recruiting CAN1012 in Pre-Malignant DCIS and LCIS · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT07702292Phase 2 · recruiting [68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Invasive Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07020806Phase 1 · recruiting [68Ga]Ga DOTA-5G as a Diagnostic Imaging Agent for Metastatic/Advanced Invasive Lobular Breast Cancer (LBC) · condition mapped CURATED_BROADER · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06033092Phase 2 · completed Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT03317405Phase 1 · active not recruiting Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery · condition mapped ONTOLOGY_EXACT · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →
→ studied in	NCT05837767NA · recruiting A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05964504recruiting Improving Survival for Metastatic Lobular Breast Cancer (PLUMB Registry) · condition mapped ALIAS · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06671912Phase 3 · suspended Testing Low Dose Tamoxifen for Invasive Breast Cancer, LoTam Trial · condition mapped ONTOLOGY_EXACT · 81 trials mapped (32 active)	—	—	Breast Lobular Carcinoma In Situ	1	Observed	clinicaltrials	graph →

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