Adult Acute Promyelocytic Leukemia

hematologic malignancy

Identifier: CI-CAN-00008690
Entity page: /cancer/adult-acute-promyelocytic-leukemia ↗
Edges: 55

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Adult Acute Promyelocytic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 27show all (up to 200)
→ investigated in trials for	Cytarabinesmall molecule 5 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adult Acute Promyelocytic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostat

Adult Acute Promyelocytic Leukemia studied in …STUDIED_INderived10 of 28show all (up to 200)
→ studied in	NCT01139970Phase 1 · completed Veliparib and Temozolomide in Treating Patients With Acute Leukemia · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT01588015Phase 1 · completed Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04897490recruiting RWE of 1st Line Treatment With ATO/ATRA for Adult APL · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01005277completed Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia · condition mapped ALIAS · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT01664897Phase 2 · completed Erlotinib Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia · condition mapped ALIAS · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT00105001Phase 2 · completed Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer · condition mapped ALIAS · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA	1	Observed	clinicaltrials	graph →
→ studied in	NCT01031368Phase 1 · completed Clofarabine, Cytarabine, and Filgrastim Followed by Infusion of Non-HLA Matched Ex Vivo Expanded Cord Blood Progenitors in Treating Patients With Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01548911Phase 2 · withdrawn Gemtuzumab Ozogamicin in Treating Patients With Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00602225Phase 1/Phase 2 · completed Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01869803approved for marketing Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic Leukemia · condition mapped ONTOLOGY_EXACT · 28 trials mapped (1 active)	—	—	Adult Acute Promyelocytic Leukemia	1	Observed	clinicaltrials	graph →

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