Acute Biphenotypic Leukemia

hematologic malignancy

Identifier: CI-CAN-00007129
Entity page: /cancer/acute-biphenotypic-leukemia ↗
Edges: 123

Neighbours: 28 drugs10 trials
Drawn: 38 of 38 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Acute Biphenotypic Leukemia investigated for …INVESTIGATED_FOR15 of 50show all (up to 200)
← investigated for	Vincristinesmall_molecule	unknown	3	Acute Biphenotypic Leukemia	1	Curated	chembl	graph →
← investigated for	Thioguaninesmall_molecule	unknown	3

Acute Biphenotypic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 32show all (up to 200)
→ investigated in trials for	Fludarabinesmall molecule 17 trials (5 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	17	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 13 trials (5 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Cytarabinesmall molecule 7 trials (3 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Venetoclaxsmall molecule 7 trials (4 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	7	Observed	clinicaltrials	graph →
→ investigated in trials for	Thiotepasmall molecule 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall molecule 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Cladribinesmall molecule 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 5 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Azacitidinesmall molecule 4 trials (2 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall_molecule 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Rituximabmonoclonal antibody 4 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Clofarabinesmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Idarubicinsmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Mitoxantronesmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Biphenotypic Leukemia	3	Observed	clinicaltrials	graph →

Acute Biphenotypic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 32show all (up to 200)

→ investigated in trials for

Fludarabinesmall molecule

17 trials (5 active) · roll-up of the cancer and its descendants

—

Acute Biphenotypic Leukemia studied in …STUDIED_INderived10 of 41show all (up to 200)
→ studied in	NCT03779854Phase 2 · active not recruiting Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03683433Phase 2 · recruiting Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04128501Phase 2 · active not recruiting Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07819396Phase 2 · not yet recruiting Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT05589896Phase 1/Phase 2 · active not recruiting A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07710781NA · not yet recruiting Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT02159495Phase 1 · active not recruiting Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT02727803Phase 2 · recruiting Personalized NK Cell Therapy in CBT · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT04975919Phase 2 · active not recruiting Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia · condition mapped CURATED_BROADER · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT03399773Phase 2 · active not recruiting Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes · condition mapped ONTOLOGY_EXACT · 41 trials mapped (14 active)	—	—	Acute Biphenotypic Leukemia	1	Observed	clinicaltrials	graph →

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