Gene
ZZEF1
zinc finger ZZ-type and EF-hand domain containing 1
Explore in graph →CI-GENE-00040260HGNC:29027 ENSG00000074755 NCBI 23140 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (19)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33585982
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021) nfib_ctf_biobank_2025 | Neurofibroma | Ssm | 7 | 38 | 18.4% | 58 | cbioportal |
| Renal Cell Carcinoma (IMmotion150 Clinical Trial, Nat Med. 2018) - iAtlas Harmonized rcc_iatlas_immotion150_2018 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.