Gene

ZNF217

zinc finger protein 217

Curated evidence

Clinical evidence (4)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–4 of 4 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
ZNF217 Overexpression4
(prognostic)	Malignant Ovarian Neoplasm	Prognostic	B	Supports Poor Outcome	3	submitted	EID12207 ZNF217 was overexpressed in 60% of ovarian tumour samples (26/44) as demonstrated by immunohistochemistry (IHC). Patients with ZNF217 expression had significantly shorter disease-free survival compare… (full text at CIViC) PMID 25031722 · Li et al., 2014 · Open in CIViC	civic
〃	Malignant Breast Neoplasm	Prognostic	D	Supports Poor Outcome	3	submitted	EID12208 ZNF217 overexpression is linked to reduced survival across multiple breast cancer subtypes. A meta-analysis of relapse-free survival across nine studies involving 858 patients revealed that higher ZNF… (full text at CIViC) PMID 22728437 · Littlepage et al., 2012 · Open in CIViC

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

gdcObserved10 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Colon Adenocarcinoma TCGA-COAD	Colon Adenocarcinoma	Ssm

Literature

Data not yet available

No publication linked to this gene yet.