TYR

tyrosinase

Explore in graph →CI-GENE-00037658HGNC:12442 ENSG00000077498 NCBI 7299 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
TYR GRCh37/hg19 11q14.3(chr11:88960991-88961138)x1601
(diagnostic)	Oculocutaneous Albinism 1BUNRESOLVED	Diagnostic	B	Supports Positive	5	rejected	EID10834 The variant is Autosomal Recessive. PMID 34980106 · Dhangar et al., 2022 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Germ Cell Tumors and Shared Leukemias (MSK, J Clin Invest 2020) gct_msk_2020	unmapped	Ssm	1	13	7.7%

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.