TYR NM_000372.5(TYR):c.1205G>A (p.Arg402Gln)

CI-VAR-00005384Explore in graph →p.Arg402GlnNM_000372.5:c.1205G>AClinVar 3779 rs1126809

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
3779	Conflicting classifications of pathogenicity; other	criteria provided, conflicting classifications	1	Oculocutaneous albinism type 1B; Temperature-sensitive oculocutaneous albinism type 1; Melanoma, cutaneous malignant, susceptibility to, 8; SKIN/HAIR/EYE PIGMENTATION 3, LIGHT/DARK SKIN; Skin/hair/eye pigmentation 3, blue/green eyes; Oculocutaneous albinism type 1A; Autosomal recessive ocular albinism; Malignant tumor of breast; Oculocutaneous albinism type 1; Albinism or congenital nystagmus; Pigmentary skin disorders; TYR-related disorder	germline	24	Jun 01, 2026	clinvar