SDHA

succinate dehydrogenase complex flavoprotein subunit A

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
SDHA R31* (c.91C>T)1
(predisposing)	Adrenal Gland Pheochromocytoma	Predisposing	C	N/A N/A	2	submitted	EID8589 Thirty-nine cases of sporadic or familial pheo/PGL and pituitary adenomas (PA) were investigated. Known pheo/PGL genes (SDHA-D, SDHAF2, RET, VHL, TMEM127, MAX, FH) and pituitary adenoma genes (MEN1, A… (full text at CIViC) PMID 25494863 · Dénes et al., 2015 · Open in CIViC	civic

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

gdcObserved39 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial ALCHEMIST-ALCH	unmapped	Ssm

Literature

Data not yet available

No publication linked to this gene yet.