RELA — gene · CancerIndex

Curated evidence

Clinical evidence (9)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–9 of 9 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CDKN2A Deletion + RELA FusionRELA CDKN2A1
(prognostic)	Supratentorial Ependymoma ZFTA Fusion-Positive	Prognostic	B	Supports Poor Outcome	3	submitted	EID11446 In a series of 54 supratentorial ependymomas with ZFTA::RELA fusions (termed fusions between C11orf95 and RELA at time of publication), homozygous deletion of CDKN2A was found in 9 cases and hemizygou… (full text at CIViC) PMID 32514758 · Jünger et al., 2020 · Open in CIViC	civic
RELA Fusion8
(diagnostic)	Supratentorial Ependymoma ZFTA Fusion-Positive	Diagnostic	A	Supports Positive	3	accepted	EID8627 Ependymoma RELA fusion-positive is a genetically defined ependymoma subtype accepted as a distinct entity in the 2016 WHO classification of CNS tumors. This variant accounts for the majority of suprat…

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

25 per page, newest first.

pubmedPublishedShowing 1–5 of 5 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.