Gene

PURB

purine rich element binding protein B

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
PURB Fusion1
Erlotinib	Lung Adenocarcinoma	Predictive	C	Supports Sensitivity Response	3	accepted	EID10996 A metastatic lung adenocarcinoma (bone and brain) was diagnosed in a 42-year-old woman (patient 3). The primary adenocarcinoma was found in left lower lobe (LLL). Her initial treatment with whole-brai… (full text at CIViC) PMID 27102076 · Konduri et al., 2016 · Open in CIViC	civic

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.
· Cancer Discov · 2016 · PMID 27102076 · validated civic_curation pubmed