PRKAR1A

protein kinase cAMP-dependent type I regulatory subunit alpha

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
PRKAR1A PRKAR1A LOH, allelic imbalance 17q1
(oncogenic)	Melanotic SchwannomaALIAS	Oncogenic	B	Supports Oncogenicity	3	submitted	EID8936 This study evaluates the genetic features of melanotic schwannoma (MS). Twelve cases of MS were examined. A hybrid capture-based next-generation sequencing (NGS) assay screened the coding exons for mu… (full text at CIViC) PMID 26031761 · Wang et al., 2015 · Open in CIViC	civic

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

gdcObserved22 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Kidney Renal Papillary Cell Carcinoma TCGA-KIRP	Papillary Renal Cell Carcinoma	Ssm

Literature

Data not yet available

No publication linked to this gene yet.