Gene
PIEZO2
piezo type mechanosensitive ion channel component 2
Explore in graph →CI-GENE-00019699HGNC:26270 ENSG00000154864 NCBI 63895 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (34)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 31792460
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Melanoma (DFCI, Nat Med. 2019) - iAtlas Harmonized mel_iatlas_liu_2019 | Melanoma | Ssm | 22 | 122 | 18% | 135 | cbioportal |
| Metastatic Melanoma (DFCI, Nature Medicine 2019) mel_dfci_2019 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.