Gene

PAX8

paired box 8

Explore in graph →CI-GENE-00018962HGNC:8622 ENSG00000125618 NCBI 7849 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
PAX8 Expression1
(diagnostic)	Malignant Female Reproductive System NeoplasmALIAS	Diagnostic	A	Supports Positive	4	accepted	EID1716 The authors explored the viability of PAX8 expression as a biomarker for differentiating mullerian from non-mullerian tumors. 74 tumors (37 Mullerian/37 non-Mullerian) were examined for PAX8 expressio… (full text at CIViC) PMID 24800185 · Heidarpour et al., 2014 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (2)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved2 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Intrahepatic Cholangiocarcinoma (Mount Sinai 2015) ihch_ismms_2015	Intrahepatic Cholangiocarcinoma	Ssm	1

Literature

Linked publications (1)

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Diagnostic utility of PAX8 in differentiation of mullerian from non-mullerian tumors.
· Adv Biomed Res · 2014 · PMID 24800185 · validated civic_curation pubmed