Gene
MPDZ
multiple PDZ domain crumbs cell polarity complex component
Explore in graph →CI-GENE-00014812HGNC:7208 ENSG00000107186 NCBI 8777 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (24)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Skin Cutaneous Melanoma TCGA-SKCM | Cutaneous Melanoma | Ssm | 335 | 470 | 71.3% | 36 | gdc |
| Non-Hodgkin Lymphoma (BCGSC, Nature 2011) nhl_bcgsc_2011 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.