Gene

MMP1

matrix metallopeptidase 1

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
MMP1 Overexpression1
Sacituzumab Govitecan	Estrogen Receptor-positive Breast CancerUNRESOLVED	Predictive	D	Supports Resistance	3	accepted	EID12597 In the TIMER dataset, levels of MMP1 is increased in cancers compared with normal tissue, where its levels in sacituzumab govitecan (SG)-resistant tumours are higher than SG-sensitive tumours by IHC. … (full text at CIViC) PMID 40287412 · Chen et al., 2025 · Open in CIViC	civic

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.