Gene
LYST
lysosomal trafficking regulator
Explore in graph →CI-GENE-00011764HGNC:1968 ENSG00000143669 NCBI 1130 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (85)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 30290956
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Bladder Cancer (MSK/TCGA, Eur Urol 2020) blca_msk_tcga_2020 | Bladder Urothelial Carcinoma | Ssm | 24 | 474 | 5.1% | 169 | cbioportal |
| Hepatocellular Carcinoma (CLCA, Nature 2024) hcc_clca_2024 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.