Gene
LRP2
LDL receptor related protein 2
Explore in graph →CI-GENE-00010495HGNC:6694 ENSG00000081479 NCBI 4036 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (200)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24336570
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Low-Grade Gliomas (UCSF, Science 2014) lgg_ucsf_2014 | Diffuse Glioma | Ssm | 5 | 61 | 8.2% | 63 | cbioportal |
| Lung Adenocarcinoma (CPTAC, Cell 2020) luad_cptac_2020 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.