Gene
LATS1
large tumor suppressor kinase 1
Explore in graph →CI-GENE-00007621HGNC:6514 ENSG00000131023 NCBI 9113 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (103)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36007103
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Endometrial Carcinoma cfDNA (MSK, Clin Cancer Res 2022) ucec_ccr_cfdna_msk_2022 | Endometrial Carcinoma | Ssm | 1 | 44 | 2.3% | 169 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, 2026) alk_msk_2026 | Lung Non-Small Cell Carcinoma | Ssm | 2 | 90 | 2.2% | 196 | cbioportal |
| High-Grade Serous Ovarian Cancer (MSK, NPJ Genome Med 2021) hgsoc_msk_2021 | High-Grade Serous Ovarian Cancer | Ssm | 1 | 45 | 2.2% | 67 | cbioportal |
| Pancreatic Acinar Cell Carcinoma (MSK, JCO 2023) paac_msk_jco_2023 | Pancreatic Acinar Cell Carcinoma | Ssm | 1 | 47 | 2.1% | 116 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.