Gene
LATS1
large tumor suppressor kinase 1
Explore in graph →CI-GENE-00007621HGNC:6514 ENSG00000131023 NCBI 9113 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (103)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38488807
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Leiomyosarcoma (MSK, Clin Cancer Res 2024) lms_msk_2024 | unmapped | Ssm | 2 | 470 | 0.4% | 161 | cbioportal |
| Gastrointestinal Stromal Tumor (MSK, NPJ Precis Oncol 2023) gist_msk_2022 | Gastrointestinal Stromal Tumor | Ssm | 2 | 499 | 0.4% | 76 | cbioportal |
| Soft Tissue Sarcoma (MSK, 2025) soft_tissue_msk_2025 | unmapped | Ssm | 1 | 422 | 0.2% | 124 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.