Gene

KLF15

KLF transcription factor 15

Explore in graph →CI-GENE-00007015HGNC:14536 ENSG00000163884 NCBI 28999 Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
KLF15 Fusion1
(diagnostic)	Myoepithelial TumorALIAS	Diagnostic	C	Supports Positive	3	accepted	EID12930 In this case report the authors described a myoepithelial carcinoma of soft tissue in a 7-week-old female infant. The tumor was located ventral to the right shoulder and measured 25 mm in diameter. Hi… (full text at CIViC) PMID 33734915 · Bodis et al., 2021 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Acute Myeloid Leukemia (TCGA GDC, 2025) aml_tcga_gdc	Acute Myeloid Leukemia	Ssm	1	72	1.4%	194

Literature

Linked publications (1)

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Myoepithelial Carcinoma of Soft Tissue With an EWSR1-KLF15 Gene Fusion in an Infant.
· Pediatr Dev Pathol · 2021 · PMID 33734915 · validated civic_curation pubmed