HSP90B1

heat shock protein 90 beta family member 1

Explore in graph →CI-GENE-00005118HGNC:12028 ENSG00000166598 NCBI 7184 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
HSP90B1 Overexpression1
Onalespib + TemozolomideCombination	Glioma	Predictive	D	Supports Sensitivity Response	2	submitted	EID10153 In vivo overexpression of HSP90 was observed in segments of the glioma-containing tissue versus the non-tumor-bearing areas in the forebrain of nude mice implanted with bioluminescent intracranial gli… (full text at CIViC) PMID 28679777 · Canella et al., 2017 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
The Metastatic Prostate Cancer Project (Provisional, June 2021) mpcproject_broad_2021	unmapped	Ssm	6	82	7.3%	54

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.