H2BC5

H2B clustered histone 5

Explore in graph →CI-GENE-00003965HGNC:4747 ENSG00000158373 NCBI 3017 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
H2BC5 Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	2	submitted	EID11949 This study reportedly sequenced 1001 DLBCL tumors using whole exome sequencing. They reported 150 recurrently mutated genes. Some concerns about the validity of the results have been expressed in subs… (full text at CIViC) PMID 28985567 · Reddy et al., 2017 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (17)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved17 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Non-Hodgkin Lymphoma (BCGSC, Nature 2011) nhl_bcgsc_2011	Non-Hodgkin Lymphoma	Ssm	2	14

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.