Gene

FOXP3

forkhead box P3

Explore in graph →CI-GENE-00002193HGNC:6106 ENSG00000049768 NCBI 50943 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
FOXP3 EXPRESSION1
Epirubicin	Malignant Breast Neoplasm	Predictive	B	Supports Sensitivity Response	4	accepted	EID928 1,097 patients with breast cancer were evaluated for FOXP3 expression by IHC. FOXP3 expression was found in 405 tumor samples and associated with improved OS in patients treated with anthracycline-bas… (full text at CIViC) PMID 22431701 · Ladoire et al., 2012 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Clear Cell Renal Cell Carcinoma (DFCI, Science 2019) ccrcc_dfci_2019	Clear Cell Renal Cell Carcinoma	Ssm	2

Literature

Linked publications (1)

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial.
· Ann Oncol · 2012 · PMID 22431701 · validated civic_curation pubmed