Gene
FGA
fibrinogen alpha chain
Explore in graph →CI-GENE-00001870HGNC:3661 ENSG00000171560 NCBI 2243 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (12)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 2 | 4 | 50% | 31 | cbioportal |
| Uterine Carcinosarcoma (Johns Hopkins, Nat Commun 2014) ucs_jhu_2014 | Uterine Malignant Mixed Mesodermal (Mullerian) Tumor | Ssm | 4 | 22 | 18.2% | 83 | cbioportal |
| Hepatocellular Carcinoma (MERiC/Basel, Nat Commun. 2022) hcc_meric_2021 | Hepatocellular Carcinoma | Ssm | 6 | 122 | 4.9% | 103 | cbioportal |
| Hepatocellular Carcinoma (CLCA, Nature 2024) hcc_clca_2024 | Hepatocellular Carcinoma | Ssm | 22 | 494 | 4.5% | 138 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.