FBXW11

F-box and WD repeat domain containing 11

Explore in graph →CI-GENE-00001759HGNC:13607 ENSG00000072803 NCBI 23291 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CTNNB1 I35T + FBXW11 F517SFBXW11 CTNNB11
(diagnostic)	Basal Cell AdenomaALIAS	Diagnostic	B	Supports Positive	4	submitted	EID12637 A comprehensive molecular profiling (whole exome and whole transcriptome sequencing) determined that CTNNB1 I35T and FBXW11 F517S missense mutations were mutually exclusive and collectively account fo… (full text at CIViC) PMID 40389436 · Wong et al., 2025 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Upper Tract Urothelial Carcinoma (IGBMC, Genome Biology 2021) utuc_igbmc_2021	Renal Pelvis and Ureter Urothelial Carcinoma	Ssm

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.