Gene
DYNC2I2
dynein 2 intermediate chain 2
Explore in graph →CI-GENE-00044091HGNC:28296 ENSG00000119333 NCBI 89891 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28196596
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Small-Cell Lung Cancer (Multi-Institute, Cancer Cell 2017) sclc_cancercell_gardner_2017 | Lung Small Cell Carcinoma | Ssm | 16 | 20 | 80% | 58 | cbioportal |
| Lung Cancer (SMC, Cancer Research 2016) lung_smc_2016 | unmapped | Ssm | 4 | 22 | 18.2% | 126 | cbioportal |
| Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga | Adrenal Cortical Carcinoma | Ssm | 11 | 90 | 12.2% | 72 | cbioportal |
| Pediatric Low-Grade Glioma (CTF, Acta Neuropathol 2021) lgg_ctf_synodos_2025 | Diffuse Glioma | Ssm | 1 | 31 | 3.2% | 178 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.