Variant · Snv
DYNC2I2 NM_052844.4(DYNC2I2):c.187-3C>A
CI-VAR-00075366Explore in graph →NM_052844.4:c.187-3C>AClinVar 474848 rs12380424
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 474848 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Short-rib thoracic dysplasia 11 with or without polydactyly; DYNC2I2-related disorder; Nonpapillary renal cell carcinoma; Cervical cancer; Familial cancer of breast; Clear cell carcinoma of kidney; Colon adenocarcinoma; Uterine corpus endometrial carcinoma; Ovarian serous cystadenocarcinoma; Cholangiocarcinoma; Uveal melanoma; Melanoma; Malignant tumor of esophagus; Acute myeloid leukemia; Colorectal cancer; Sarcoma; Gastric cancer; Lymphoma | germline | 4 | Feb 02, 2026 | clinvar |