Gene

CDX2

caudal type homeobox 2

Curated evidence

Clinical evidence (2)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CDX2 EXPRESSION2
(prognostic)	Malignant Colorectal NeoplasmCURATED_BROADER	Prognostic	B	Supports Better Outcome	4	accepted	EID956 Patients with stage II/III colorectal cancer were analyzed for expression of CDX2 (by microarray and IHC). In the discovery (466 patients) and validation sets (314 patients), 5-year DFS was lower amon… (full text at CIViC) PMID 26789870 · Dalerba et al., 2016 · Open in CIViC	civic
〃	Malignant Colon Neoplasm	Prognostic	B	Supports Better Outcome	4	rejected	EID1130 In patients with stage II colon cancer, positive CDX2 status was associated with longer overall survival. PMID 26789877 · Boland et al., 2016 · Open in CIViC

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.