Variant · Expression
CDX2 EXPRESSION
CI-VAR-00000934Explore in graph →CIViC 410
Curated evidence
Evidence by cancer (2 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26789877
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Malignant Colon Neoplasm1 | ||||||||
| CDX2 EXPRESSION | (prognostic) | Prognostic | B | Supports Better Outcome | 4 | rejected | EID1130In patients with stage II colon cancer, positive CDX2 status was associated with longer overall survival. PMID 26789877 · Boland et al., 2016 · Open in CIViC | civic |
| Malignant Colorectal Neoplasm1 | ||||||||
| CDX2 EXPRESSION | (prognostic) | Prognostic | B | Supports Better Outcome | 4 | accepted | EID956Patients with stage II/III colorectal cancer were analyzed for expression of CDX2 (by microarray and IHC). In the discovery (466 patients) and validation sets (314 patients), 5-year DFS was lower amon… (full text at CIViC) PMID 26789870 · Dalerba et al., 2016 · Open in CIViC | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available