Gene
CACNA1S
calcium voltage-gated channel subunit alpha1 S
Explore in graph →CI-GENE-00032158HGNC:1397 ENSG00000081248 NCBI 779 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (43)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 35982973
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Squamous Cell Carcinoma (UOW, Front Oncol 2022) cscc_ranson_2022 | Skin Squamous Cell Carcinoma | Ssm | 17 | 25 | 68% | 145 | cbioportal |
| Uterine Corpus Endometrial Carcinoma TCGA-UCEC |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.