Gene
CACNA1A
calcium voltage-gated channel subunit alpha1 A
Explore in graph →CI-GENE-00032142HGNC:1388 ENSG00000141837 NCBI 773 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (95)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32220886
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer (MSK, Clinical Cancer Res 2020) brca_pareja_msk_2020 | Invasive Breast Carcinoma | Ssm | 3 | 60 | 5% | 135 | cbioportal |
| Bladder Cancer (MSK/TCGA, Eur Urol 2020) blca_msk_tcga_2020 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.