BCL11B

BCL11 transcription factor B

Explore in graph →CI-GENE-00021719HGNC:13222 ENSG00000127152 NCBI 64919 Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
BCL11B Fusion1
(diagnostic)	T Acute Lymphoblastic LeukemiaCURATED_BROADER	Diagnostic	C	Supports Positive	3	submitted	EID8564 TLX3, also known as HOX11L2 is a homeobox gene, located on the long arm of chromosome 5. TLX3 is not expressed in normal T-cell development. In this paper, the authors described a "new" cryptic transl… (full text at CIViC) PMID 11587205 · Bernard et al., 2001 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (20)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved20 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Non-Small Cell Lung Cancer (MSK, Science 2015) nsclc_mskcc_2015	Lung Non-Small Cell Carcinoma	Ssm	3

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.