Gene

BAIAP2L1

BAR/IMD domain containing adaptor protein 2 like 1

Explore in graph →CI-GENE-00021601HGNC:21649 ENSG00000006453 NCBI 55971 Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
BAIAP2L1 Fusion1
PD173074	Bladder Carcinoma	Predictive	D	Supports Sensitivity Response	3	accepted	EID144 Following identification of this fusion in a patient, this fusion was expressed in HEK 293T cells leading to oligomerization in the absence of ligand, induced morphologic changes in the cell and incre… (full text at CIViC) PMID 23558953 · Wu et al., 2013 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Acute Myeloid Leukemia (TCGA GDC, 2025) aml_tcga_gdc	Acute Myeloid Leukemia	Ssm	1	72	1.4%	56

Literature

Linked publications (1)

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Identification of targetable FGFR gene fusions in diverse cancers.
· Cancer Discov · 2013 · PMID 23558953 · validated civic_curation pubmed