Gene

B4GALT1

beta-1,4-galactosyltransferase 1

Explore in graph →CI-GENE-00021551HGNC:924 ENSG00000086062 NCBI 2683 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
B4GALT1 Overexpression1
(prognostic)	Renal Cell CarcinomaCURATED_BROADER	Prognostic	B	Supports Poor Outcome	3	accepted	EID1278 438 patients with non-metastatic clear-cell renal carcinoma were were retrospectively analysed for B4GALT1 expression via IHC. High B4GALT1 expression was associated with poor overall survival (P<0.00… (full text at CIViC) PMID 27092876 · Xie et al., 2016 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (2)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved2 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017	Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Literature

Linked publications (1)

25 per page, newest first.

pubmedPublishedShowing 1–1 of 1 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Increased B4GALT1 expression associates with adverse outcome in patients with non-metastatic clear cell renal cell carcinoma.
· Oncotarget · 2016 · PMID 27092876 · validated civic_curation pubmed