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Drugs
One entity per molecule (INN preferred); brand names and development codes are aliases. Approvals are always shown with jurisdiction and indication.
820 drugs
| Drug | Kind | Mechanism | Approvals | Evidence items | Trials | Identifiers |
|---|---|---|---|---|---|---|
| Anti-CD33 | — | — | 0 | 2 | 0 | — |
| Anti-ErbB3 Monoclonal Antibody AV-203 | — | — | 0 | 2 | 1 | C102535 |
| Anti-PD-1 Monoclonal Antibody MEDI0680 | — | — | 0 | 2 | 3 | C113332 |
| Bazedoxifene | Small Molecule | Estrogen receptor modulator | 0 | 2 | 2 | C73598 · CHEMBL46740 |
| BET Inhibitor | — | — | 0 | 2 | 0 | C128462 |
| BPTES | — | — | 0 | 2 | 0 | — |
| Camonsertib | Small Molecule | — | 0 | 2 | 8 | C174206 · CHEMBL5095260 |
| Carboplatin/Paclitaxel Regimen | — | — | 0 | 2 | 59 | C63402 |
| Carboplatin/Pemetrexed Regimen | — | — | 0 | 2 | 3 | C136284 |
| Cediranib | Small Molecule | Stem cell growth factor receptor inhibitor; Platelet-derived growth factor receptor inhibitor; Vascular endothelial growth factor receptor inhibitor | 0 | 2 | 100 | C80867 · CHEMBL491473 |
| Checkpoint Kinase Inhibitor AZD7762 | — | — | 0 | 2 | 3 | C66961 |
| Chk1 Inhibitor | — | — | 0 | 2 | 0 | C155927 |
| Copanlisib | Small Molecule | PI3-kinase p110-alpha subunit inhibitor; PI3-kinase p110-delta subunit inhibitor | 0 | 2 | 72 | C96796 · CHEMBL3218576 |
| CTX-712 | — | — | 0 | 2 | 1 | — |
| Derazantinib | Small Molecule | Fibroblast growth factor receptor inhibitor | 0 | 2 | 4 | C104267 · CHEMBL4297187 |
| Elimusertib | Small Molecule | Serine-protein kinase ATR inhibitor | 0 | 2 | 10 | C146807 · CHEMBL4647810 |
| EPZ011989 | Small Molecule | — | 0 | 2 | 0 | CHEMBL3672841 |
| Firmonertinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor | 0 | 2 | 52 | C180535 · CHEMBL4297258 |
| FLT3 Inhibitor FF-10101 Succinate | — | — | 0 | 2 | 1 | C137988 |
| FOLFIRI Regimen | — | — | 0 | 2 | 136 | C63593 |
| Ganetespib | Small Molecule | Heat shock protein HSP90 inhibitor | 0 | 2 | 31 | C77872 · CHEMBL2103879 |
| Ganitumab | Monoclonal Antibody | Insulin-like growth factor I receptor antagonist | 0 | 2 | 27 | C71531 · CHEMBL1743024 |
| HDAC Inhibitor REC-2282 | — | — | 0 | 2 | 4 | C116850 |
| Hematopoietic Cell Transplantation | — | — | 0 | 2 | 13 | C15431 |
| Imlunestrant Regimen | — | — | 0 | 2 | 0 | C222429 |
| Inhibitor | — | — | 0 | 2 | 0 | C154898 |
| Izorlisib | Small Molecule | PI3-kinase class I inhibitor | 0 | 2 | 4 | C158603 · CHEMBL1684984 |
| JQ-1 | Small Molecule | — | 0 | 2 | 0 | CHEMBL1957266 |
| JSI-124 | — | — | 0 | 2 | 0 | — |
| L19IL2 | — | Fibronectin binding agent | 0 | 2 | 5 | CHEMBL2109608 |
| Lometrexol | Small Molecule | — | 0 | 2 | 2 | C979 · CHEMBL34412 |
| Lunresertib | Small Molecule | — | 0 | 2 | 4 | C179323 · CHEMBL5199076 |
| Masitinib | Small Molecule | Fibroblast growth factor receptor 3 inhibitor; Stem cell growth factor receptor inhibitor; Platelet-derived growth factor receptor inhibitor | 0 | 2 | 18 | C79910 · CHEMBL1908391 |
| Mocetinostat | Small Molecule | Histone deacetylase 1 inhibitor; Histone deacetylase 2 inhibitor; Histone deacetylase 3 inhibitor; Histone deacetylase 11 inhibitor; Histone deacetylase 8 inhibitor | 0 | 2 | 18 | C62521 · CHEMBL272980 |
| Motesanib | Small Molecule | Stem cell growth factor receptor inhibitor; Tyrosine-protein kinase receptor RET inhibitor; Vascular endothelial growth factor receptor inhibitor; Platelet-derived growth factor receptor inhibitor | 0 | 2 | 21 | C71896 · CHEMBL572881 |
| Nab-paclitaxel | — | — | 0 | 2 | 754 | C2688 |
| Navtemadlin | Small Molecule | Tumour suppressor p53/oncoprotein Mdm2 inhibitor | 0 | 2 | 18 | C116624 · CHEMBL3125702 |
| NSC348884 | — | — | 0 | 2 | 0 | — |
| NSC84167 | — | — | 0 | 2 | 0 | — |
| Omacetaxine Mepesuccinate | Small Molecule | Protein synthesis inhibitor | 0 | 2 | 34 | C1127 · CHEMBL46286 |
| Palbociclib Regimen | — | — | 0 | 2 | 0 | C160808 |
| Pan-AKT Kinase Inhibitor GSK690693 | — | — | 0 | 2 | 2 | C71711 |
| PD-1 Ligand Inhibitor | — | — | 0 | 2 | 1 | C156893 |
| Pidnarulex | Small Molecule | — | 0 | 2 | 7 | C126798 · CHEMBL4303309 |
| Prexasertib | Small Molecule | Serine/threonine-protein kinase Chk1 inhibitor; Serine/threonine-protein kinase Chk2 inhibitor | 0 | 2 | 19 | C91392 · CHEMBL3544911 |
| Quarfloxin | Small Molecule | — | 0 | 2 | 4 | C71726 · CHEMBL3989407 |
| R-CHOP Regimen | — | — | 0 | 2 | 2 | C63452 |
| Rebemadlin | — | — | 0 | 2 | 0 | C74594 |
| Retaspimycin Hydrochloride | Small Molecule | Heat shock protein HSP90 inhibitor | 0 | 2 | 10 | C48401 · CHEMBL377559 |
| Rezatapopt | Small Molecule | — | 0 | 2 | 3 | C203051 · CHEMBL5314538 |